Burden of Pneumonia-Associated Hospitalizations – United States, 2001-2014.

Link to article at PubMed

Burden of Pneumonia-Associated Hospitalizations - United States, 2001-2014.

Chest. 2017 Oct 07;:

Authors: Hayes BH, Haberling DL, Kennedy J, Varma JK, Fry AM, Vora NM

BACKGROUND: The epidemiology of pneumonia has likely evolved in recent years, reflecting an aging population, changes in population immunity, and socioeconomic disparities.
METHODS: Using the National (Nationwide) Inpatient Sample (NIS), estimated numbers and rates of pneumonia-associated hospitalizations for 2001-2014 were calculated. A pneumonia-associated hospitalization was defined as one in which the discharge record listed a principal diagnosis of pneumonia or a secondary diagnosis of pneumonia if the principal diagnosis was respiratory failure or sepsis.
RESULTS: There were an estimated 20,361,181 (SE: 95,601) pneumonia-associated hospitalizations in the United States during 2001-2014 (average annual age-adjusted pneumonia-associated hospitalization rate of 464.8 per 100,000 population [95% CI: 462.5-467.1]). The average annual age-adjusted pneumonia-associated hospitalization rate decreased over the study period. In-hospital death occurred in 7.4% (SE: 0.03) of pneumonia-associated hospitalizations. Non-Hispanic American Indian/Alaskan Natives and non-Hispanic blacks had the highest average annual age-adjusted rates of pneumonia-associated hospitalization of all race/ethnicities at 439.2 (95% CI: 415.9-462.5) and 438.6 (95% CI: 432.5-444.7) per 100,000 population, respectively. During 2001-2014, the proportion of pneumonia-associated hospitalizations co-listing an immunocompromising condition increased from 18.7% (SE: 0.2) in 2001 to 29.5% (SE: 0.2) in 2014. Total charges for pneumonia-associated hospitalizations in 2014 were over $84 billion.
CONCLUSIONS: Pneumonia is a major cause of morbidity and mortality in the United States. Differences in rates and outcomes of pneumonia-associated hospitalizations between sociodemographic groups warrant further investigation. The immunocompromised population has emerged as a group experiencing a disproportionate burden of pneumonia-associated hospitalizations.

PMID: 29017956 [PubMed - as supplied by publisher]

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