Reversal of Warfarin Era Thinking.
J Intern Med. 2017 Oct 05;:
Authors: Shatzel JJ, Daughety MM, Prasad V, DeLoughery TG
Anticoagulation offers benefits in appropriately selected patients, however, all anticoagulants increase the risk of bleeding, which can be, at times, life threatening. For decades, vitamin K antagonists were the only oral anticoagulants available to physicians and their patients. In recent years, we have witnessed the approval of five direct oral anticoagulants (DOACs), which have shifted prior paradigms in anticoagulation such as omitting the need for routine therapeutic monitoring and lessening concerns about food and drug interactions. This article is protected by copyright. All rights reserved.
PMID: 28981174 [PubMed - as supplied by publisher]