National Trends (2007-2013) of Clostridium difficile Infection in Patients with Septic Shock: Impact on Outcome.
J Hosp Med. 2017 Sep;12(9):717-722
Authors: Chatterjee K, Goyal A, Chada A, Kakkera KS, Corwin HL
BACKGROUND: Clostridium difficile is the most common infectious cause of healthcare-associated diarrhea and is associated with worse outcomes and higher cost. Patients with septic shock (SS) are at increased risk of acquiring C. difficile infections (CDIs) during hospitalization, but little data are available on CDI complicating SS.
OBJECTIVE: Prevalence of CDI in SS between 2007-2013 and impact of CDI on outcomes in SS.
METHODS: Outcomes were prevalence of CDI in SS, effect on mortality, length of stay (LOS), and 30-day readmission.
RESULTS: There were 2,031,739 hospitalizations with SS (2007-2013). CDI was present in 8.2% of SS. The in-hospital mortality of SS with and without CDI were comparable (37.1% vs 37.0%;