Thrombotic thrombocytopenic purpura: The role of ADAMTS13.
Cleve Clin J Med. 2016 Aug;83(8):597-603
Authors: Rogers HJ, Allen C, Lichtin AE
Abstract
Thrombotic thrombocytopenic purpura (TTP) is an uncommon, life-threatening disease requiring prompt diagnosis and initiation of therapeutic plasma exchange to improve patient survival. However, diagnosis is often difficult because of atypical presentations and signs and symptoms that resemble other conditions. Measurements of ADAMTS13 activity, ADAMTS13 inhibitor, and ADAMTS13 autoantibody are useful for diagnosing TTP, guiding therapy, and predicting relapse.
PMID: 27505881 [PubMed - as supplied by publisher]