Zika Virus Infection Associated with Severe Thrombocytopenia.
Clin Infect Dis. 2016 Jul 14;
Authors: Sharp TM, Muñoz-Jordán J, Perez-Padilla J, Bello-Pagán MI, Rivera A, Pastula DM, Salinas JL, Martínez Mendez JH, Méndez M, Powers AM, Waterman S, Rivera-García B
We report two patients who developed severe thrombocytopenia after Zika virus infection. The first had 1,000 platelets/mm(3), and died following multiple hemorrhages. The second had 2,000 platelets/mm(3), melena, ecchymoses, and recovered after receiving intravenous immunoglobulin. Physicians should be aware that Zika virus may be associated with immune-mediated severe thrombocytopenia.
PMID: 27418575 [PubMed - as supplied by publisher]