Efficacy of Oral Vancomycin in Preventing Recurrent Clostridium Difficile Infection in Patients Treated with Systemic Antimicrobial Agents.
Clin Infect Dis. 2016 Jun 17;
Authors: Van Hise NW, Bryant AM, Hennessey EK, Crannage AJ, Khoury JA, Manian FA
Abstract
We compared the rates of recurrent Clostridium difficile infection in patients receiving with those not receiving oral vancomycin prophylaxis when treated with systemic antimicrobial therapy. The incidence of Clostridium difficile infection was significant lower in patients receiving prophylaxis (4.2% vs 26.6%, O.R. 0.12, 95% C.I. 0.04 to 0.4, P<0.0001).
PMID: 27318333 [PubMed - as supplied by publisher]