Tentative nil per os leads to poor outcomes in older adults with aspiration pneumonia.

Link to article at PubMed

Tentative nil per os leads to poor outcomes in older adults with aspiration pneumonia.

Clin Nutr. 2015 Oct 9;

Authors: Maeda K, Koga T, Akagi J

BACKGROUND & AIMS: Patients with aspiration pneumonia (AP) may experience swallowing function declines during treatment, necessitating artificial feeding methods. Proper AP treatment contributes to maintaining activities of daily living. The aim was to assess the effect of tentative nil per os (NPO) status on the recovery of AP patients and declines in their swallowing abilities.
METHODS: In this retrospective cohort study, 331 patients with AP having oral food intake in premorbid status were included after exclusions for reasons such as vomiting or respiratory insufficiency. We divided subjects into 2 groups: an early oral intake (EOI) group and a tentative NPO group according to the directions by the attending doctors at admission. We created a population model related to groupings from all subjects, which was a homoscedastic model without statistical differences by the inverse probability of treatment weighted (IPTW) method and compared outcomes between the groups.
RESULTS: In the IPTW model, tentative NPO status resulted in poorer nutritional intake every day for 1 week from the date of admission (p < 0.05), a significantly longer treatment duration (50% treatment length: NPO group, 13 days [95% confidence interval (CI), 12.04-13.96] and EOI group, 8 days [95% CI, 7.69-8.31 [log-rank test, p < 0.001]) and greater decline in swallowing ability over the course of treatment (p < 0.001).
CONCLUSIONS: Tentative NPO status with AP at hospital admission resulted in adverse effects on patients, including prolonged treatment duration and declines in swallowing ability. Avoiding unnecessary NPO might be another method to treat AP and contribute to the patient's outcomes in addition to medication administration.

PMID: 26481947 [PubMed - as supplied by publisher]

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