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The association of gasping and outcome, in out of hospital cardiac arrest: A systematic review and meta-analysis.
Resuscitation. 2015 Sep 23;
Authors: Zhao-Master L, Li C, Liu B, Wang M, Shao-Master R, Fang Y
Abstract
OBJECTIVE: Gasping is common after cardiac arrest, and its frequency decreases over time. The aim of this study was to conduct a meta-analysis to evaluate the association of gasping and survival to discharge in patients who suffered out-of-hospital cardiac arrest.
METHODS: Relevant studies were identified by searching in PubMed, Medline, Embase, OVID, Web of Science and Google Scholar. Risk ratios (RR) and 95% confidence intervals (CI) were calculated to assess the association of gasping and on out-of-hospital cardiac arrest outcomes. Heterogeneity, subgroup analysis, sensitivity analysis and publication bias were explored.
RESULTS: Individual patient data was obtained from 10797 participants suffered out-of-hospital cardiac arrest in five cohort studies of 4 articles. A fixed effects model suggested that patients with gasping were 3.525 times (95% CI: 3.028- 4.104; P<0.01) more likely to survive to discharge than those without gasping, and there was no heterogeneity among studies (P=0.564). Also it may be a favorable factor for return of spontaneous circulation (RR: 2.170; 95% CI: 1.691, 2.785) with high heterogeneity (Q= 5.26; P=0.022).
CONCLUSIONS: Findings of this meta-analysis demonstrated that gasping is common after cardiac arrest, and is associated with increased survival to discharge. Patients who are cardiac arrest with gasping should be promptly resuscitated.
PMID: 26409219 [PubMed - as supplied by publisher]