Fever of Unknown Origin: A Clinical Approach.
Am J Med. 2015 Jun 17;
Authors: Cunha BA, Lortholary O, Cunha CB
Abstract
Fevers of unknown origin remain one of the most difficult diagnostic challenges in medicine. Since fever of unknown origin may be caused by over two hundred malignant/neoplastic, infectious, rheumatic/inflammatory, and miscellaneous disorders clinicians often order non-clue based imaging and specific testing early in the fever of unknown origin workup which may be inefficient/misleading. Unlike other most fever of unknown origin reviews, this article presents a clinical approach. Characteristic history and physical examination findings together with key non-specific test abnormalities are the basis for a focused clue directed fever of unknown origin workup.
PMID: 26093175 [PubMed - as supplied by publisher]