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Clonal analysis of Staphylococcus hominis strains isolated from hospitalized patients.
Pol J Microbiol. 2014;63(3):349-54
Authors: Szczuka E, Trawczyński K, Kaznowski A
Abstract
Staphylococcus hominis is a part of normal skin flora, but it is also a cause of nosocomial infections. The aim of this study was to investigate the genetic relatedness of 62 strains of S. hominis obtained from hospitalised patients during an 11-year period. For the discrimination of these clinical strains we used repetitive sequence-based PCR method (BOX-PCR) and multiple-locus variable-number tandem repeat analysis (MLVA). BOX-PCR analysis revealed a large genetic diversity among clinical strains and we did not find a predominant clone with the ability to persist in a hospital environment. MLVA is not as discriminatory as BOX fingerprinting and would not be a useful method for epidemiological studies.
PMID: 25546946 [PubMed - indexed for MEDLINE]