Diagnostic approach to von Willebrand disease.

Link to article at PubMed

Diagnostic approach to von Willebrand disease.

Blood. 2015 Feb 23;

Authors: Ng C, Motto DG, Di Paola J

Von Willebrand Disease (VWD) is one of the most common inherited bleeding disorders, with a prevalence of symptomatic disease of approximately 1/10,000. Given the complexity of the disease, the ability to accurately and appropriately diagnose individuals with VWD continues to be an important and much discussed topic of interest. For the clinician, the diagnosis of VWD is important in order to identify, assign to a subtype, and treat individuals with VWD. For the researcher, the varied spectrum of VWD and increasing understanding of Von Willebrand Factor (VWF) biology allow for continued investigation into novel mechanisms to diagnosis, categorize, and understand the underlying pathophysiology in patients with VWD. In this review, we highlight the current status of clinical testing and diagnostic classifications that are useful to the clinician while also underscoring the current limitations of the existing tests.

PMID: 25712990 [PubMed - as supplied by publisher]

Leave a Reply

Your email address will not be published.