Hepatopulmonary syndrome.

Link to article at PubMed

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Hepatopulmonary syndrome.

Clin Liver Dis. 2014 May;18(2):407-20

Authors: Koch DG, Fallon MB

The hepatopulmonary syndrome (HPS) is a pulmonary complication of cirrhosis and/or portal hypertension whereby patients develop hypoxemia as a result of alterations in pulmonary microvascular tone and architecture. HPS occurs in up to 30% of patients with cirrhosis. Although the degree of hypoxemia does not reliably correlate with the severity of liver disease, patients with HPS have a higher mortality than do patients with cirrhosis without the disorder. There has been progress into defining the mechanisms that lead to hypoxemia in HPS, but to date there are no therapeutic options for HPS aside from liver transplantation.

PMID: 24679503 [PubMed - indexed for MEDLINE]

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