Antibiotic-resistant gram-negative bacterial infections in patients with cancer.
Clin Infect Dis. 2014 Nov 15;59 Suppl 5:S335-9
Authors: Perez F, Adachi J, Bonomo RA
Patients with cancer are at high risk for infections caused by antibiotic resistant gram-negative bacteria. In this review, we summarize trends among the major pathogens and clinical syndromes associated with antibiotic resistant gram-negative bacterial infection in patients with malignancy, with special attention to carbapenem and expanded-spectrum β-lactam resistance in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia-all major threats to our cancer patients. Optimal therapy for these antibiotic-resistant pathogens still remains to be determined.
PMID: 25352627 [PubMed - in process]