Portal Hypertension – Pathophysiology, Diagnosis and Management.

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Portal Hypertension - Pathophysiology, Diagnosis and Management.

Intern Med J. 2014 Sep 17;

Authors: Bloom S, Kemp W, Lubel J

Portal hypertension is an important complication of liver disease, although other conditions may also be implicated. As a result of elevated pressures within the portal vein a number of complications can arise including the development of oesophageal and gastric varices, ascites, hepatic encephalopathy as well as complications secondary to circulatory dysfunction such as hepatorenal syndrome, portopulmonary syndrome and hepatopulmonary syndrome. This review outlines the pathogenesis and diagnosis of portal hypertension and outlines the management of these various important clinical sequelae. The management of oesophageal and gastric varices is particularly important and both the emergency management together with prophylactic management of this condition are described.

PMID: 25230084 [PubMed - as supplied by publisher]

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