Norovirus Infection in Immunocompromised Hosts.
Clin Microbiol Infect. 2014 Jul 9;
Authors: Green KY
Abstract
Acute gastroenteritis caused by the noroviruses (NV) is often of 2-3 days duration and is characteristically self-limiting. In contrast, chronic infection caused by noroviruses in immunocompromised individuals can last from weeks to years, making clinical management difficult. The mechanisms by which noroviruses establish persistent infection, and the role of immunocompromised hosts as a reservoir for noroviruses in the general human population are not known. However, study of this patient cohort may lead to new insights into norovirus biology and approaches to treatment. This article is protected by copyright. All rights reserved.
PMID: 25040790 [PubMed - as supplied by publisher]