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Catheter-related bloodstream infections caused by Trichosporon species.
Southeast Asian J Trop Med Public Health. 2014 Mar;45(2):421-9
Authors: Issarachaikul R, Lertwannawit O, Detporntewan P, Uaprasert N, Plongla R, Shuangshoti S, Chindamporn A, Suankratay C
Abstract
Trichosporonosis is an emerging invasive opportunistic fungal infection in immunocompromised patients. We report 5 catheter related blood stream infections caused by Trichosporon species over a five-year period at King Chulalongkorn Memorial Hospital, Bangkok, Thailand. All the patients were immunocompromised, had received broad-spectrum antibiotics and had a central venous catheter or arterial line inserted for a mean duration of 16.2 days (range 10-30 days). Four patients developed disseminated infection and only 2 survived, giving a mortality rate of 60%. Because of the prevalence of Trichosporon catheter related blood stream infections at our institute, health care providers should have a high index of suspicion for Trichosporon species infections in patients with risk factors and prolonged presence of a central venous catheter.
PMID: 24968684 [PubMed - indexed for MEDLINE]