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Causes and Pathophysiology of Heart Failure with Preserved Ejection Fraction.
Heart Fail Clin. 2014 Jul;10(3):389-398
Authors: Kovács A, Papp Z, Nagy L
Abstract
Heart failure with preserved ejection fraction (HFPEF) is frequently associated with multiple disorders complicating both the clinical management and the understanding of the underlying mechanisms. This review focuses on the causes and pathophysiology of HFPEF and overviews how cellular and molecular changes related to various comorbidities may influence the age-dependent and gender-dependent hemodynamic alterations of diastolic ventricular function.
PMID: 24975903 [PubMed - as supplied by publisher]