The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move.

Link to article at PubMed

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The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move.

Clin Microbiol Infect. 2014 Mar 13;

Authors: Valiente E, Cairns MD, Wren BW

Abstract
Clostridium difficile is a Gram positive, spore forming, human and animal pathogen that is the major cause of antibiotic-associated diarrhoea worldwide. The past decade has seen the rapid emergence of the hypervirulent PCR ribotype (RT) 027 complex which has been associated with an increased, incidence, severity of disease and mortality. In this review, we describe the potential virulence factors that have been reported in strains from the RT 027 complex. We review the emergence, population structure, dissemination and evolution of this lineage This article is protected by copyright. All rights reserved.

PMID: 24621128 [PubMed - as supplied by publisher]

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