Host immunological response and factors associated with clinical outcome in patients with the novel influenza A H7N9 infection.
Clin Microbiol Infect. 2013 Dec 18;
Authors: Shen Z, Chen Z, Li X, Xu L, Guan W, Cao Y, Hu Y, Zhang J
In March 2013, an influenza outbreak caused by a novel avian-origin H7N9 influenza A virus emerged in eastern China [1,2]. This H7N9 virus has not been detected from humans or animals previously. Genetic analysis revealed that the viral genome consisted of six internal genes from avian influenza A (H9N2) viruses whereas the haemagglutinin (HA) and neuraminidase (NA) gene segments derive from viruses from ducks or wild birds. Patients usually presented with fever and cough, with early sputum production, and the illness progressed rapidly to severe pneumonia, moderate-to-severe acute respiratory distress syndrome (ARDS) and shock . Up to July, this novel influenza A virus has caused infection in 134 individuals in China This article is protected by copyright. All rights reserved.
PMID: 24350809 [PubMed - as supplied by publisher]