Clinical Characteristics Predicting Early Clinical Failure After 72 hours of Antibiotic Treatment in Women with Community-Onset Acute Pyelonephritis: A Prospective Multicenter Study.

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Clinical Characteristics Predicting Early Clinical Failure After 72 hours of Antibiotic Treatment in Women with Community-Onset Acute Pyelonephritis: A Prospective Multicenter Study.

Clin Microbiol Infect. 2013 Dec 12;

Authors: Wie SH, Ki M, Kim J, Cho YK, Lim SK, Lee JS, Kwon KT, Lee H, Cheong HJ, Park DW, Ryu SY, Chung MH, Pai H

Abstract
Acute pyelonephritis (APN) is an upper urinary tract infection characterized by inflammation of the renal parenchyma and renal pelvis typically due to a bacterial infection ascending from the bladder. APN is a common bacterial infection in the community, especially in otherwise healthy women. It has been estimated that women are almost five times as likely as men to be hospitalized for APN (11.7/10,000 vs. 2.4/10,000) [1,2]. In South Korea, the annual incidence of APN is 35.7 per 10,000 people, with the rate of hospitalization for APN being 9.96 per 10,000 women and 1.18 per 10,000 men [3]. Several factors such as frequency of sexual intercourse in the previous 30 days, diabetes mellitus, urinary incontinence, and a family history of urinary tract infections have been shown to increase the risk of APN [4,5] This article is protected by copyright. All rights reserved.

PMID: 24330047 [PubMed - as supplied by publisher]

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