Biomarkers in acute respiratory distress syndrome.
Curr Opin Crit Care. 2013 Nov 27;
Authors: Binnie A, Tsang JL, Dos Santos CC
PURPOSE OF REVIEW: The article provides an overview of efforts to identify and validate biomarkers in acute respiratory distress syndrome (ARDS) and a discussion of the challenges confronting researchers in this area.
RECENT FINDINGS: Although various putative biomarkers have been investigated in ARDS, the data have been largely disappointing and the 'troponin' of ARDS remains elusive. Establishing a relationship between measurable biological processes and clinical outcomes is vital to advancing clinical trials in ARDS and expanding our arsenal of treatments for this complex syndrome.
SUMMARY: This article summarizes the current status of ARDS biomarker research and provides a framework for future investigation.
PMID: 24296379 [PubMed - as supplied by publisher]