At-Risk Drinking Is Independently Associated With ICU and 1-Year Mortality in Critically Ill Nontrauma Patients.

Link to article at PubMed

Related Articles

At-Risk Drinking Is Independently Associated With ICU and 1-Year Mortality in Critically Ill Nontrauma Patients.

Crit Care Med. 2013 Nov 6;

Authors: Gacouin A, Tadie JM, Uhel F, Sauvadet E, Fillâtre P, Letheulle J, Bouju P, Le Tulzo Y

OBJECTIVES:: The impact of at-risk drinking on the outcomes of nontrauma patients is not well characterized. The aim of this study was to determine whether at-risk drinking is independently associated with the survival of nontrauma patients in an ICU and within 1 year following ICU discharge.
DESIGN:: Observational cohort study.
SETTING:: A 21-bed mixed ICU in a university hospital.
PATIENTS:: A total of 662 patients who experienced an ICU stay of 3 days or more and for whom alcohol consumption could be assessed.
MEASUREMENTS AND MAIN RESULTS:: ICU-related variables were collected prospectively, and a 1-year follow-up was determined retrospectively. Analyses were adjusted based on prognostic determinants of short- and long-term outcomes, as previously described in ICU patients and alcohol abusers. Two hundred and eight patients (33%) were identified as at-risk drinkers according to the National Institute on Alcohol Abuse and Alcoholism criteria. Additionally, 111 patients (17%) died in the ICU, and 97 (15%) died after ICU discharge. From the ICU admission until the end of the 1-year follow-up period, the at-risk drinkers exhibited poorer survival than the non-at-risk drinkers (p = 0.0004, as determined by the log-rank test). More specifically, 50 at-risk drinkers (24%) versus 61 non-at-risk drinkers (13%) died in the ICU (p = 0.0009 for the comparison). After adjustment, at-risk drinking remained independently associated with mortality in the ICU (adjusted odds ratio of 1.83; 95% CI of 1.16-2.89; p = 0.01) and with mortality within the year following ICU discharge (adjusted hazard ratio of 1.70; 95% CI of 1.15-2.52; p = 0.008). The causes of death in the at-risk and non-at-risk drinkers were similar.
CONCLUSIONS:: In this population of critically ill nontrauma patients, at-risk drinking was independently associated with death in the ICU and within the year following ICU discharge.

PMID: 24201172 [PubMed - as supplied by publisher]

Leave a Reply

Your email address will not be published.