Higher Persistence in Newly Diagnosed Nonvalvular Atrial Fibrillation Patients Treated With Dabigatran Versus Warfarin.
Circ Cardiovasc Qual Outcomes. 2013 Aug 6;
Authors: Zalesak M, Siu K, Francis K, Yu C, Alvrtsyan H, Rao Y, Walker D, Sander S, Miyasato G, Matchar D, Sanchez H
BACKGROUND: <2) or with a higher bleed risk (HEMORR2HAGES>3) had a higher likelihood of nonpersistence (hazard ratios, 1.1; 95% confidence interval, 1.0-1.3; P=0.02; and hazard ratios, 1.2; 95% confidence interval, 1.1-1.4; P=0.004).Conclusions-Patients who initiated dabigatran treatment were more persistent than patients who began warfarin treatment. Within each cohort, patients with lower stroke risk were more likely to discontinue therapy.
PMID: 23922182 [PubMed - as supplied by publisher]