New Anticoagulant and Antiplatelet Agents: A Primer for the Gastroenterologist.
Clin Gastroenterol Hepatol. 2013 Jun 1;
Authors: Baron TH, Kamath PS, McBane RD
Abstract
A large number of patients worldwide receive anticoagulant and antiplatelet agents, collectively known as antithrombotic agents. Several new anticoagulants and antiplatelet agents have recently been approved for use. Gastroenterologists may be unfamiliar with the mechanism of action, indications for use, and pharmacokinetics of these newer drugs. In patients undergoing elective and urgent endoscopic procedures clinicians must be familiar with these medications to optimize outcomes. When the decision is made to continue the newer antithrombotic agents for elective procedures, the clinician must understand the risk of bleeding that these agents may impart on procedural-induced bleeding. Finally, it is important to understand how to manage these agents in the setting in the presence of acute gastrointestinal bleeding. In this article the use of newer antithrombotic agents will be reviewed.
PMID: 23735447 [PubMed - as supplied by publisher]