Does Empirical Therapy with a Fluoroquinolone or the Combination of a ?-Lactam Plus a Macrolide Result in Better Outcomes for Patients Admitted to the General Ward?

Link to article at PubMed

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Does Empirical Therapy with a Fluoroquinolone or the Combination of a β-Lactam Plus a Macrolide Result in Better Outcomes for Patients Admitted to the General Ward?

Infect Dis Clin North Am. 2013 Mar;27(1):115-32

Authors: Ruhe J, Mildvan D

Abstract
Community-acquired pneumonia (CAP) is a frequent cause of morbidity and mortality in the United States and worldwide, in particular among older patients and those with significant comorbid conditions. Current guidelines recommend therapy with a fluoroquinolone or a β-lactam plus a macrolide for the treatment of hospitalized adults with CAP who do not require admission to an intensive care unit. This article provides a brief summary and overview of the existing literature on this topic categorized by the main results; the potential implications for future clinical practice and research are discussed.

PMID: 23398869 [PubMed - in process]

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