Safety of ultrasound-guided thoracentesis in patients with abnormal preprocedural coagulation parameters.

Link to article at PubMed

Safety of ultrasound-guided thoracentesis in patients with abnormal preprocedural coagulation parameters.

Chest. 2013 Mar 14;

Authors: Hibbert RM, Atwell TD, Lekah A, Patel MD, Carter RE, McDonald JS, Rabatin JT

Abstract

ABSTRACT BACKGROUND: Despite a low incidence of hemorrhagic complications following thoracentesis, correction or attempted correction of abnormal preprocedural coagulation parameters is still commonly performed. We aimed to assess hemorrhagic complications following ultrasound-guided thoracentesis in patients with abnormal preprocedural coagulation parameters. METHODS: We analyzed 1,009 ultrasound-guided thoracenteses performed between January 2005 and September 2011 on patients with international normalized ratio (INR) greater than 1.6, serum platelet values less than 50 x 109/L, or both. Procedures were divided into two groups: those in whom abnormal preprocedural coagulation parameters were not corrected before the thoracentesis (Group 1) and a second group in which patients received a transfusion of platelets or fresh frozen plasma prior to thoracentesis (Group 2). All procedures were evaluated for hemorrhagic complications as defined by the National Institutes of Health Common Terminology Criteria for Adverse Events. RESULTS: A total of 1,009 ultrasound-guided thoracenteses were included in our study consisting of 706 procedures in 538 patients in Group 1 and 303 procedures in 235 patients in Group 2. There were four hemorrhagic complications out of 1,009 procedures (0.40%, 95% CI: 0.15% to 1.02%), zero in Group 1 (0/706 or 0.0%; 95% CI: 0% to 0.68%) and four in Group 2 (4/303 or 1.32 %; 95% CI: 0.51% to 3.36%). CONCLUSIONS: Hemorrhagic complications are infrequent after ultrasound-guided thoracentesis and attempting to correct an abnormal INR or platelet level before the procedure is unlikely to confer any benefit. We consider the procedure safe in patients with abnormal preprocedural parameters when performed by expert personnel.

PMID: 23493971 [PubMed - as supplied by publisher]

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