Diagnostic management of acute deep vein thrombosis and pulmonary embolism.
J Thromb Haemost. 2013 Jan 7;
Authors: Huisman M, Klok F
Acute deep vein thrombosis (DVT) and pulmonary embolism (PE) represent two expressions of a similar clinical pathological process, often referred to as venous thromboembolism (VTE). It has long been recognized that, as clinical signs and symptoms of PE and DVT are not specific for the diagnosis, objective diagnosis in both patients presenting with leg as well as with chest symptoms is mandatory. Since the last review in this journal on this subject in 2009, several large trials have been performed that shed new light on all aspects of the diagnostic management of suspected VTE, especially in the field of simplified clinical decision rules, age-dependent D-dimer cut offs and magnetic resonance imaging. © 2013 International Society on Thrombosis and Haemostasis.
PMID: 23294863 [PubMed - as supplied by publisher]