New anticoagulants for treatment of venous thromboembolism.

Link to article at PubMed

Related Articles

New anticoagulants for treatment of venous thromboembolism.

Eur J Intern Med. 2012 Oct 22;

Authors: Franchini M, Mannucci PM


Venous thromboembolism (VTE) is a major cause of morbidity and mortality and anticoagulation is the cornerstone of treatment. Although effective, traditional anticoagulants (i.e., heparins and vitamin K antagonists) have significant limitations and there are several unmet needs. Therefore, new drugs have been developed, including direct factor Xa inhibitors (e.g., rivaroxaban, apixaban and edoxaban) and thrombin inhibitors (e.g., dabigatran etexilate). The characteristics of these agents and the main results of published clinical studies dealing with VTE treatment are critically summarized in this article.

PMID: 23095463 [PubMed - as supplied by publisher]

Leave a Reply

Your email address will not be published. Required fields are marked *