Glucose in the ICU – Evidence, Guidelines, and Outcomes.

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Glucose in the ICU - Evidence, Guidelines, and Outcomes.

N Engl J Med. 2012 Sep 7;

Authors: Kavanagh BP


Just over a decade ago, a single-center Belgian study showed that normalization of blood glucose in critically ill patients lowered hospital mortality by more than 30%.(1) Although subsequent studies were unable to reproduce these findings, the appeal of such a straightforward intervention was too great to resist: guidelines from professional organizations(2),(3) were published, and editorial commentary(4) highlighted initiatives by the Institute for Healthcare Improvement, the Joint Commission on Accreditation of Healthcare Organizations, and the Volunteer Hospital Association that incorporated tight glucose control as a standard. Indeed, the prestigious Codman Award of the Joint Commission was presented in 2004 for . . .

PMID: 22957522 [PubMed - as supplied by publisher]

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