How to diagnose and phenotype asthma.
Clin Chest Med. 2012 Sep;33(3):445-57
Authors: Nair P, Dasgupta A, Brightling CE, Chung KF
Asthma has been described as a chronic disease of the airways characterized by variable airflow obstruction, airway hyperresponsiveness, and airway inflammation. This review discusses the diagnosis and phenotyping of asthma, with a special emphasis on phenotyping based on the nature of cellular inflammation and radiological imaging and how this could be used to direct the treatment of asthma and, in the future, to apply specifically directed therapies to specific phenotypes.
PMID: 22929094 [PubMed - in process]