The role of peritoneal dialysis in the treatment of ascites.
Nefrologia. 2011 Nov 25;31(6):648-55
Authors: Ros Ruiz S, Gutiérrez Vilchez E, García Frías TP, Martín Velázquez TM, Blanca Martos L, Jiménez Salcedo T, Hernández Marrero D
Cirrhosis represents a late stage of hepatic fibrosis and leads to high morbidity and mortality, and the most frequent complication is ascites. Only a few patients with advanced cirrhosis have 'refractory ascites' and do not respond to conventional treatment. Repeated paracentesis for evacuation is considered the treatment of choice in these cases. A large proportion of these patients have associated chronic kidney disease (CKD), which may require renal replacement therapy (RRT). Due to the complications associated with liver disease with coagulation disorders and tendencies towards spontaneous hypotension, there are significant problems associated to RRT, especially haemodialysis (HD). On the contrary, peritoneal dialysis (PD) offers several advantages over HD in cirrhotic patients (with or without ascites) thanks to better haemodynamic tolerance, as it is a continuous and slow technique. Furthermore, PD has a low rate of infection and bleeding.
PMID: 22130279 [PubMed - indexed for MEDLINE]