Risk stratification and short-term prognosis in acute heart failure syndromes: a review of novel biomarkers.
Biomarkers. 2011 Aug;16(5):379-92
Authors: Avellino A, Collins SP, Fermann GJ
BACKGROUND: Early risk stratification of patients with acute heart failure syndrome (AHFS) can guide the decision to admit the patient to hospital and the choice of therapy.
METHODS: Standard review methodology using Medline and Google scholar from the years 2006-present. Papers before 2006 were reviewed when necessary.
RESULTS: Biomarkers used in AHFS are broadly classified based on their mechanism of action: inflammation, renal stress, extracellular matrix remodeling, oxidative stress, cardiac myocyte stress, and neurohormonal regulation.
CONCLUSION: This paper provides a review for clinicians and medical scientists highlighting the most recent advances in biomarkers with application in AHFS.
PMID: 21534728 [PubMed - indexed for MEDLINE]