Antimicrobial Prescribing Practices in Response to Different Clostridium difficile Diagnostic Methodologies.

Link to article at PubMed

Antimicrobial Prescribing Practices in Response to Different Clostridium difficile Diagnostic Methodologies.

Infect Control Hosp Epidemiol. 2011 Nov;32(11):1133-6

Authors: Sydnor ER, Lenhart A, Trollinger B, Avdic E, Maragakis LL, Carroll KC, Cosgrove SE

Abstract
We evaluated treatment decisions and antimicrobial use related to 2 testing algorithms for Clostridium difficile infection (CDI). Our findings suggest that a 2-step testing algorithm using rapid polymerase chain reaction confirmatory testing leads to decreased unnecessary anti-CDI antimicrobial use. In addition, a significant proportion of patients with confirmed CDI were not treated according to recommended guidelines.

PMID: 22011545 [PubMed - in process]

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