Fosfomycin: an old-new antibiotic.
Clin Microbiol Infect. 2011 Jul 18;
Authors: Raz R
Clin Microbiol Infect 2011 ABSTRACT: Fosfomycin is a broad-spectrum antibiotic discovered in Spain in 1969. It has bactericidal activity against a wide range of bacteria, including gram-negative micro-organisms and some gram-positive bacteria, such as staphylococci. Initially fosfomycin was administered parenterally and only to patients with severe infections. Today it is often dispensed as fosfomycin-trometamol, an oral formula recommended in the treatment of urinary tract infections. Fosfomycin-trometamol in a single dose is indicated for the treatment of women with uncomplicated urinary tract infections.
PMID: 21914036 [PubMed - as supplied by publisher]