Susceptibility of Staphylococcus aureus to vancomycin: analysis of minimum inhibitory concentrations in two tertiary care hospitals in eastern South Dakota.
S D Med. 2011 Mar;64(3):91-5
Authors: Laible BR, Hellwig TR, Hedge DD
Vancomycin has been considered the accepted standard of therapy for methicillin-resistant Staphylococcus aureus (MRSA) and is commonly used as an alternative for methicillin-suceptible Staphylococcus aureus (MSSA) in cases of allergy or intolerance to other agents. MRSA strains exhibiting elevated vancomycin MICs (minimum inhibitory concentration) within the susceptible range have been associated with increased treatment failure and mortality. The aim of our study was to evaluate for evidence of elevated vancomycin MICs among S. aureus isolates associated with pneumonia or skin/soft tissue infection (SSTI) in our adult inpatient population.
PMID: 21473519 [PubMed - in process]