Comparative effectiveness of diuretic regimens.
N Engl J Med. 2011 Mar 3;364(9):877-8
Authors: Fonarow GC
Acute decompensated heart failure is associated with substantial morbidity, mortality, and health care expenditures.(1) Most patients present with symptoms related to fluid overload, which may be complicated by concomitant renal dysfunction.(2) Treating the signs and symptoms of heart failure while preserving or improving renal function is a crucial therapeutic goal. For more than five decades, the administration of intravenous loop diuretics has been the mainstay of therapy to reduce congestion, decrease ventricular filling pressures, and improve symptoms of heart failure, with such therapy becoming an empirically accepted standard of care for this condition.(1),(3),(4) However, there is little evidence . . .
PMID: 21366480 [PubMed - in process]