Factor Xa inhibitors for acute coronary syndromes.

Link to article at PubMed

Factor Xa inhibitors for acute coronary syndromes.

Cochrane Database Syst Rev. 2011;1:CD007038

Authors: Brito V, Ciapponi A, Kwong J

The activation of coagulation mechanisms plays a central role in the pathogenesis of acute coronary syndromes (ACS). Administration of unfractionated heparin (UFH) and low molecular weight heparins (LMWH), agents preventing the progression of thrombus formation, is a crucial therapeutic strategy. However, some limitations related to their use have recently stimulated the development of new synthetic agents.

PMID: 21249686 [PubMed - in process]

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