Treatment of hypertension in patients 80 years and older: the lower the better? A meta-analysis of randomized controlled trials.
J Hypertens. 2010 Jul;28(7):1366-72
Authors: Bejan-Angoulvant T, Saadatian-Elahi M, Wright JM, Schron EB, Lindholm LH, Fagard R, Staessen JA, Gueyffier F
Results of randomized controlled trials are consistent in showing reduced rates of stroke, heart failure and cardiovascular events in very old patients treated with antihypertensive drugs. However, inconsistencies exist with regard to the effect of these drugs on total mortality.
PMID: 20574244 [PubMed - indexed for MEDLINE]