Stem cells in sepsis and acute lung injury.
Crit Care Med. 2010 Dec;38(12):2379-85
Authors: Cribbs SK, Matthay MA, Martin GS
Sepsis and acute lung injury continue to be major causes of morbidity and mortality worldwide despite advances in our understanding of pathophysiology and the discovery of new management strategies. Recent investigations show that stem cells may be beneficial as prognostic biomarkers and novel therapeutic strategies in these syndromes. This article reviews the potential use of endogenous adult tissue-derived stem cells in sepsis and acute lung injury as prognostic markers and also as exogenous cell-based therapy.
PMID: 20838330 [PubMed - indexed for MEDLINE]