Emerging carbapenemases: a global perspective.
Int J Antimicrob Agents. 2010 Nov;36S3:S8-S14
Authors: Walsh TR
The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of this general increase is the unbridled dissemination of carbapenem resistance genes, namely KPC, OXA and metallo-?-lactamase variants. In particular, the media attention given to the NDM-1 metallo-?-lactamase has highlighted the global consequences of human behaviour on spreading antibiotic resistance.
PMID: 21129630 [PubMed - as supplied by publisher]