A review on the putative association between Beta-blockers and depression.
Heart Fail Clin. 2011 Jan;7(1):89-99
Authors: Verbeek DE, van Riezen J, de Boer RA, van Melle JP, de Jonge P
Several kinds of systematic studies have been conducted verifying the putative association between ?-blockers and depressive symptoms. However, many of these studies had important limitations in their design. In most of the studies, no effect of ?-blockers on depressive symptoms was seen. Because individual susceptibility cannot be ruled out, clinicians must stay vigilant, especially with patients who have a positive personal or family history and who have been prescribed lipophilic ?-blockers. However, fear for depression should not be the reason for reluctance in prescribing ?-blockers to cardiovascular patients.
PMID: 21109212 [PubMed - in process]