Drug-induced acute kidney injury in the critically ill adult: recognition and prevention strategies.
Crit Care Med. 2010 Jun;38(6 Suppl):S169-74
Authors: Bentley ML, Corwin HL, Dasta J
Acute kidney injury is common in critically ill patients, with an incidence of 20% to 30%. It has been associated with increased mortality, hospital length of stay, and total cost. A number of strategies may be beneficial in identifying at-risk patients. In addition, using preventive measures and avoiding nephrotoxic medications are paramount in reducing the overall incidence. Although multifactorial, drug-induced acute kidney injury may account for up to 25% of all cases of acute kidney injury in this population. This review focuses on the mechanisms of drug-induced acute kidney injury in critically ill adults and offers preventive strategies when appropriate.
PMID: 20502171 [PubMed - in process]