Oral formulations of budesonide: a novel treatment for inflammatory bowel disease.
Drugs Today (Barc). 2008 Nov;44(11):857-63
Authors: Svoboda RP, Patel DH, Olden KW
Budesonide is a promising drug for a variety of documented applications and has potential in gastroenterology. Its unique local mechanism of delivery and efficient first-pass metabolism, resulting in fewer systemic adverse effects than with conventional glucocorticoids, makes this a desirable drug for clinical practice. This drug has shown promise in treating a wide spectrum of inflammatory diseases from inflammatory bowel disease and other colitides to autoimmune liver diseases. Future research should focus on ways to increase delivery methods to promote long-term usage for maintenance therapy for the disease entities listed above, as well as for other potential nongastrointestinal conditions.
PMID: 19180263 [PubMed - indexed for MEDLINE]