Presentation and diagnosis of primary biliary cirrhosis in the 21st century.

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Presentation and diagnosis of primary biliary cirrhosis in the 21st century.

Clin Liver Dis. 2008 May;12(2):243-59; vii

Authors: Kumagi T, Onji M

Primary biliary cirrhosis is a slowly progressive, cholestatic, and chronic liver disease in which the epithelium of the intrahepatic biliary tree is destroyed by a chronic inflammatory process. The origin of this disease, which mainly affects middle-aged women, is unknown but has characteristics favoring an autoimmune etiology. This article reviews the presentation and diagnosis of PBC in the 21st century.

PMID: 18456178 [PubMed - indexed for MEDLINE]

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