Positive end-expiratory pressure in acute respiratory distress syndrome: should the 'open lung strategy' be replaced by a 'protective lung strategy'?
Crit Care. 2007;11(6):180
Authors: Rouby JJ, Ferrari F, Bouhemad B, Lu Q
In patients with acute respiratory distress syndrome, positive end-expiratory pressure is associated with alveolar recruitment and lung hyperinflation despite the administration of a low tidal volume. The best positive end-expiratory pressure should correspond to the best compromise between recruitment and distension, a condition that coincides with the best respiratory elastance.
PMID: 18086329 [PubMed - indexed for MEDLINE]